Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils

E. Jablonska; M. Marcinczyk

doi:10.1080/0962935031000134905

Mediators of Inflammation (Jan 2003)

Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils

E. Jablonska,
M. Marcinczyk

Affiliations

E. Jablonska: Department of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, Poland
M. Marcinczyk: Department of Immunology, Medical University of Bialystok, Waszyngtona 15A, Bialystok 15-274, Poland

DOI: https://doi.org/10.1080/0962935031000134905
Journal volume & issue: Vol. 12, no. 3
pp. 179 – 183

Abstract

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Background: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal neutrophils. It has been reported that IL-18-induced cytokine production may be significantly enhanced by coincident addition of IL-15.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://www.hindawi.com/journals/mi/

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