Journal of Fundamental and Applied Sciences (Jun 2014)

THERMODYNAMIC PARAMETERS OF SOLUTIONS OF SILDENAFIL CITRATE IN SOME ORGANIC SOLVENTS AT DIFFERENT TEMPERATURES

  • S. Baluja,
  • K. Bhesaniya

Journal volume & issue
Vol. 6, no. 1
pp. 106 – 115

Abstract

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The solubility of Sildenafil citrate in some organic solvents; hexane, toluene,1-butanol and 1,2 dichloroethane has been determined using gravimetric method over different temperature range (298.15 K to 328.15 K) at one atmospheric pressure. The modified Apelblat and Buchowski-Ksiazczak λh equations were used to correlate the experimental solubility data. Further, various thermodynamic parameters have been evaluated from these solubility data.