Skin testing and challenge in patients with immediate hypersensitivity reactions to gadolinium-based contrast agents identify safe future options

• Florian Stehlin,
• Rabea Y. Khoudja,
• Derek Lee,
• Jean-Francois Toupin,
• Ghislaine A.C. Isabwe,
• Michael Fein,
• Ibtihal Al-Otaibi,
• Elizabeth J. Phillips,
• Jason A. Trubiano,
• Ana-Maria Copaescu

Affiliations

Florian Stehlin

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada; Division of Clinical Immunology and Allergy, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland; The Research Institute of McGill University Health Centre, McGill University, Montreal, Canada; Corresponding author. Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada.

Rabea Y. Khoudja

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada; The Research Institute of McGill University Health Centre, McGill University, Montreal, Canada

Derek Lee

Pharmacy Department, Montreal General Hospital, Montreal, Canada

Jean-Francois Toupin

Department of Diagnostic Radiology, McGill University Health Centre (MUHC), McGill University, Montreal, Canada

Ghislaine A.C. Isabwe

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada; The Research Institute of McGill University Health Centre, McGill University, Montreal, Canada

Michael Fein

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada

Ibtihal Al-Otaibi

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada; Division of Allergy and Clinical Immunology, Department of Paediatrics, Central Second Health Cluster, Ministry of Health, Riyadh, Saudi Arabia; College of Medicine, Princess Noura Bint Abdulrahman University, Riyadh, Saudi Arabia

Elizabeth J. Phillips

Center for Drug Safety and Immunology, Vanderbilt University Medical Centre, Nashville, USA; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia

Jason A. Trubiano

Center for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, Australia; The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Parkville, Australia; Department of Infectious Diseases, University of Melbourne, At the Peter Doherty Institute for Infection and Immunity, Victoria, Australia

Ana-Maria Copaescu

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre (MUHC), McGill University, Montreal, Canada; The Research Institute of McGill University Health Centre, McGill University, Montreal, Canada; Center for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, Australia; Department of Infectious Diseases, University of Melbourne, At the Peter Doherty Institute for Infection and Immunity, Victoria, Australia