Archives of Biological Sciences (Jan 2011)

Extended time of cold ischemia and its influence on the physiological function of human adult pancreatic islets

  • Nikolić D.M.,
  • Đorđević P.B.,
  • Radak Đ.,
  • Lačković Vesna B.,
  • Bajčetić Miloš I.,
  • Milić Gordana,
  • Gostiljac D.,
  • Ilić M.,
  • Raketić Nevenka,
  • Stojiljković Vesna,
  • Grubor Nikica M.,
  • Jovanović M.D.,
  • Latinčić S.M.

DOI
https://doi.org/10.2298/ABS1104007N
Journal volume & issue
Vol. 63, no. 4
pp. 1007 – 1013

Abstract

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In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we established that there are no major differences between these two test groups and that the storage and transport of pancreatic tissue in physiological solution at 4oC gives quite satisfactory results.

Keywords