Preaxial Polydactyly of the Foot: Variable Expression of Trisomy 13 in a Case from Central Africa

Sébastien Mbuyi-Musanzayi; Aimé Lumaka; Bienvenu Yogolelo Asani; Toni Lubala Kasole; Prosper Lukusa Tshilobo; Prosper Kalenga Muenze; François Tshilombo Katombe; Koenraad Devriendt

doi:10.1155/2014/365031

Case Reports in Genetics (Jan 2014)

Preaxial Polydactyly of the Foot: Variable Expression of Trisomy 13 in a Case from Central Africa

Sébastien Mbuyi-Musanzayi,
Aimé Lumaka,
Bienvenu Yogolelo Asani,
Toni Lubala Kasole,
Prosper Lukusa Tshilobo,
Prosper Kalenga Muenze,
François Tshilombo Katombe,
Koenraad Devriendt

Affiliations

Sébastien Mbuyi-Musanzayi: Department of Surgery, University Hospital, University of Lubumbashi, P.O. Box 1825, Lubumbashi, Democratic Republic of Congo
Aimé Lumaka: Center for Human Genetics, University Hospitals, KU Leuven, UZ Leuven, Campus Gasthuisberg, Herestraat 49, P.O. Box 602, 3000 Leuven, Belgium
Bienvenu Yogolelo Asani: Center for Human Genetics, Faculty of Medicine, University of Lubumbashi, P.O. Box 1825, Lubumbashi, Democratic Republic of Congo
Toni Lubala Kasole: Center for Human Genetics, Faculty of Medicine, University of Lubumbashi, P.O. Box 1825, Lubumbashi, Democratic Republic of Congo
Prosper Lukusa Tshilobo: Center for Human Genetics, University Hospitals, KU Leuven, UZ Leuven, Campus Gasthuisberg, Herestraat 49, P.O. Box 602, 3000 Leuven, Belgium
Prosper Kalenga Muenze: Center for Human Genetics, Faculty of Medicine, University of Lubumbashi, P.O. Box 1825, Lubumbashi, Democratic Republic of Congo
François Tshilombo Katombe: Department of Surgery, University Hospital, University of Lubumbashi, P.O. Box 1825, Lubumbashi, Democratic Republic of Congo
Koenraad Devriendt: Center for Human Genetics, University Hospitals, KU Leuven, UZ Leuven, Campus Gasthuisberg, Herestraat 49, P.O. Box 602, 3000 Leuven, Belgium

DOI: https://doi.org/10.1155/2014/365031
Journal volume & issue: Vol. 2014

Abstract

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Trisomy 13 is a chromosomal disorder characterized by a severe clinical picture of multiple congenital anomalies. We here describe the clinical and genetic features and prognosis observed in a newborn with trisomy 13 from Central Africa. He presented the rare feature of preaxial polydactyly of the feet.

Published in Case Reports in Genetics

ISSN: 2090-6544 (Print); 2090-6552 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://onlinelibrary.wiley.com/journal/4918

About the journal