F1000Research (Jun 2019)

Recent advances in endometrial cancer: a review of key clinical trials from 2015 to 2019 [version 1; peer review: 2 approved]

  • Lindsey M. Charo,
  • Steven C. Plaxe

DOI
https://doi.org/10.12688/f1000research.17408.1
Journal volume & issue
Vol. 8

Abstract

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In the past few years, we have seen several important advances in understanding of and therapy for endometrial cancer. This review highlights key recent abstracts and publications in endometrial cancer from 2015 to 2019. We focus on clinical trials in surgical staging and the utility of sentinel lymph node mapping, adjuvant treatment for high-risk disease and HER2/neu-positive serous tumors, combination therapy for recurrent disease, molecular biology, and immunotherapy.