Klinik Psikiyatri Dergisi (Jun 2020)

Validity and reliability of the Turkish version of the Glasgow antipsychotic side effect scale (tur)

  • Esma Akpınar Aslan,
  • Sedat Batmaz,
  • Özgür Ahmet Yüncü,
  • Neslihan Sevil,
  • Burcu Erkek

DOI
https://doi.org/10.5505/kpd.2020.94547
Journal volume & issue
Vol. 23, no. 3
pp. 290 – 301

Abstract

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INTRODUCTION[|]Regular and comprehensive follow-up of the side effects of antipsychotic drugs is an essential part of the treatment process. Self-report scales which are user friendly and which do not take too much time to complete are required. The aim of this study was to adapt the Glasgow Antipsychotic Side Effect Scale (GASS) into Turkish, and to evaluate its validity and reliability.[¤]METHODS[|]For this study, patients over the age of 18 presenting to the outpatient psychiatry clinics of secondary healthcare facilities in three different cities were recruited. Two hundred and ninety-seven of these patients who were on at least one antipsychotic drug except for clozapine for at least three months and who were diagnosed with any psychiatric disorders, and fifty-six patients of them were not on any antipsychotic drug treatment. The patients completed the GASS and the Systematic Monitoring of Adverse events Related to TreatmentS (SMARTS). The clinicians completed a demographic and clinical data form and the Clinical Global Impression Scale (CGI). Exploratory factor analysis was undertaken and concurrent validity, discriminating validity, internal consistency, test – retest reliability, and responsiveness of the GASS were calculated.[¤]RESULTS[|]Results demonstrated that the GASS consisted of seven factors,that it had concurrent validity with the SMARTS and the CGI (rho=0.706 & 0.381 respectively,p's<0.001),that it could discriminate between patients who were on and who were not on antipsychotics(U=14357.50,p<0.001),that it had internal consistency(Cronbach's α=0.775) and test–retest reliability(intraclass correlation coefficient=0.964,p<0.001),that it had responsiveness,and that the minimal clinically important difference was 5 points.[¤]DISCUSSION AND CONCLUSION[|]In conclusion, the Turkish version of the GASS was shown to be a valid and reliable scale. The GASS may enable clinicians to question the side effects experienced by patients who are on antipsychotic drugs comprehensively and systematically in a short time and to identify and follow-up the severity of the symptoms and their response to treatment.[¤]

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