Journal of Saudi Chemical Society (Sep 2016)

[Bmim]BF4 ionic liquid: An efficient reaction medium for the one-pot multi-component synthesis of 2-amino-4,6-diphenylpyridine-3-carbonitrile derivatives

  • S. Sheik Mansoor,
  • K. Aswin,
  • K. Logaiya,
  • S.P.N. Sudhan

DOI
https://doi.org/10.1016/j.jscs.2012.07.011
Journal volume & issue
Vol. 20, no. 5
pp. 517 – 522

Abstract

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One-pot condensation from aromatic aldehyde, methyl ketone, malononitrile and ammonium acetate in the presence of the ionic liquid (IL), 1-butyl-3-methylimidazolium tetrafluoroborate ([Bmim][BF4]), affords the corresponding 2-amino-4,6-diphenylpyridine-3-carbonitrile derivatives. This method has the advantage of short routine, high yields and being environmentally-friendly. Here, the need for catalyst is avoided through the use of catalytically active ionic liquid as solvent. Furthermore, the possible mechanism is also proposed.

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