Communications Biology (Feb 2021)

Photoreceptor metabolic reprogramming: current understanding and therapeutic implications

  • Warren W. Pan,
  • Thomas J. Wubben,
  • Cagri G. Besirli

DOI
https://doi.org/10.1038/s42003-021-01765-3
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 16

Abstract

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Photoreceptor death is central to vision loss in various retinal diseases. Disruption of nutrient availability and cell metabolism may underlie photoreceptor death. In this review, Pan et al. focus on the recent advances in the understanding of photoreceptor metabolism and suggest novel targets for neuroprotective strategies that prevent blindness.