A CASE OF EXTRANODAL NK/T-CELL LYMPHOMA PRESENTING WITH EOSINOPHILIA

Abstract

Background. Eosinophilia can occur in extranodal NK/T-cell lymphoma. Chronic hypereosinophilia from any cause is associated with endomyocardial fibrosis.Methods and material. This report includes on a patient with hypereosinophilia, which was diagnosed and investigated nine months before the diagnosis of extranodal NK/T-cell lymphoma (nasal type) of the larynx was confirmed by biopsy. He died with signs of heart failure 11 months after the first symptoms developed. Post mortem investigation revealed endomyocardial fibrosis as a result of chronic hypereosinophilia.Conclusions. To our knowledge eosinophilia has not previously been reported in extranodal NK/T-cell lymphoma (nasal type). Therefore, this is considered to be a rare feature of the presented case. Investigation of the heart for potential silent complications of prolonged and severe eosinophilia has to be considered at an early stage

Keywords

• eosinophilia
• extranodal NK/T-cell lymphoma
• endomyocardial fibrosis