Thiadiazines, <em>N</em>,<em>N</em>-Heterocycles of Biological Relevance

Abstract

The 3,5-disubstituted tetrahydro-2<em>H</em>-1,3,5-thiadiazine-2-thione scaffold has found many applications in recent years. This review is aimed at highlighting the most important aspects of these compounds: Synthesis, spectroscopic characterization and biological activities. How the chemical nature of N-substituents influences the overall activity and cytotoxicity profile will also be discussed.

Keywords

• heterocycles
• thiadiazines
• synthesis and biological activity