Metabolites (Nov 2023)

Controlling Nutritional Status Score as a Predictor for Chronic Obstructive Pulmonary Disease Exacerbation Risk in Elderly Patients

  • Aurelio Lo Buglio,
  • Giulia Scioscia,
  • Francesco Bellanti,
  • Pasquale Tondo,
  • Piera Soccio,
  • Matteo Pio Natale,
  • Donato Lacedonia,
  • Gianluigi Vendemiale

DOI
https://doi.org/10.3390/metabo13111123
Journal volume & issue
Vol. 13, no. 11
p. 1123

Abstract

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The Controlling Nutritional Status (CONUT) score is a simple screening tool able to assess poor nutritional status as well as to predict clinical adverse outcomes in different clinical settings. No data are available in older patients with chronic obstructive pulmonary disease (COPD). This study aimed to investigate the CONUT score as a predictor of frequent exacerbations. We retrospectively enrolled 222 patients aged 65 years or older, classified in two groups according to the number of exacerbations (or hospitalizations because AECOPD) during the previous year. The two groups were further divided according to low (p < 0.001) of the occurrence of ≥2 exacerbations (or 1 hospitalization) during the previous year. The CONUT score seemed to have a high prognostic value for frequent exacerbations for COPD in older patients. The predictive role of different CONUT score cut-off values needs to be validated in larger COPD populations in future multi-center, prospective clinical studies.

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