APIK Journal of Internal Medicine (Jan 2023)

A study of electrolyte imbalance in Coronavirus Disease-2019 at a rural tertiary health care center

  • R Sheeba,
  • Dinesh Kumar Vishwanathan,
  • Vasantha Kamath

DOI
https://doi.org/10.4103/ajim.ajim_113_22
Journal volume & issue
Vol. 11, no. 3
pp. 185 – 190

Abstract

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Background: With the ongoing onslaught of coronavirus disease-2019 (COVID-19) pandemic, identifying factors predicting the disease course and outcome become immensely important. Although globally reported, a potential association between electrolyte disturbance and COVID-19 disease has not been well researched. Dyselectrolytemia not only impacts patient care but also provides insight into the pathophysiology of COVID-19. Aims and Objectives: Our aim was to study electrolyte disturbances among COVID-19 patients and its impact on the disease outcome. Materials and Methods: This was a retrospective observational study conducted in a total of 397 patients detected to have electrolyte abnormalities among 2914 adult inpatients, diagnosed with COVID 19 infection in a tertiary care center over a period of 10 months (July 2020–December 2020 and April 2021–July 2021). Results: A total of 2914 patients were diagnosed with COVID-19 of whom 397 (13.62%) patients were found to have an electrolyte imbalance. Hyponatremia (n = 199) 51% was the most common electrolyte disturbance followed by hypokalemia (n = 94) 24.3% and mixed electrolyte abnormality (n = 81) 20.4%. Electrolyte imbalance was directly related to the clinical outcome of the disease which was statistically significant P = 0.0001. Conclusion: Hyponatremia has a significant direct correlation with mortality in patients with COVID-19. However, hypokalemia, hyperkalemia, and hypernatremia also influence the disease outcome. We recommend that the estimation of electrolytes should be done routinely for all hospitalized patients with COVID-19 as it adds to the prognostication of these patients.

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