A Promising Future for Prostate Cancer Diagnostics

Abstract

It has been estimated that globally there is a death attributable to prostate cancer every four minutes. As life expectancy in all world regions increases, so too incidence of this disease of the ageing male will increase. For many men diagnosis occurs after presentation with symptoms of altered urinary dynamics. Unfortunately, these changes, whilst also associated with benign disease, are evident quite late in the aetiology of prostate cancer. Early detection provides for better management and prognosis. This Special Issue provides an up to date view of the advances made towards early diagnosis and prognosis. It provides reviews of advanced imaging techniques (e.g., multiparametric MRI and protocols), and of biomaterials and molecular biomarkers currently being explored (e.g., microRNAs, proteomics) and the technologies that are revolutionizing this field. It describes the multi-disciplinary approaches that are essential to inexpensive, deliverable and accurate platforms for prostate cancer diagnostics.

Keywords

• PI-RADS
• diffusion weighted imaging
• 223RaCl2
• [18F]-NaF PET/CT
• PERCIST
• circulating tumour cells
• oncosomes
• oncosomal DNAs and RNAs
• quantum dot multiplex arrays
• carbon nanotube technologies