Correlation of androgen receptor with ultrasound, clinicopathological features and clinical outcomes in breast cancer

Abstract

Key points In terms of clinicopathology, the probability of AR expression in different subtypes of breast cancer was various, and the positive expression of AR was associated with lower histological grade and lower Ki-67 level. In terms of ultrasound, the positive expression of AR was associated with unsmooth margin, posterior acoustic shadowing and stiffer on strain elastography, and AR + and AR– tumors performed differently when analyzed separately according to different molecular subtypes. The positive expression of AR could be a sign of a better prognosis in breast cancer.

Keywords

• Breast cancer
• Androgen receptor
• Ultrasound
• Nomogram
• Prognosis