Medicina v Kuzbasse (Jun 2024)

IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION

  • Алексей Андреевич Шмелев,
  • Алексей Геннадьевич Тришкин,
  • Антон Игоревич Лесников,
  • Лилия Владиславовна Курганова,
  • Алексей Дмитриевич Бушмакин,
  • Алексей Сергеевич Ильин

Journal volume & issue
Vol. 23, no. 2
pp. 68 – 71

Abstract

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The immunological factor is one of the causes of male infertility. If there is a significant amount of sperm in the ejaculate that is sensitive to antisperm antibodies (ASAT), the ability to fertilize may be impaired. Antibodies directed against sperm components have a negative effect on various processes before and after fertilization. Objective – to identify the prevalence of the immunological factor in men of the Kemerovo region. Compare the spermogram indicators in men with different indicators of the MAR test. Results. It was found out that out of 1827 men with infertility, a positive MAR test was detected in 116, which was 6.35 % of the sample. The negative effect of ASAT on concentration and progressive mobility was demonstrated in the comparison group between a high (90-100 %) and normal (less than 40 %) MAR test index. Conclusion. The prevalence of the immunological factor of infertility in Kuzbass men has been revealed. A difference was found between the indicators of concentration and progressive motility of spermatozoa in the groups with normal and high values of the MAR test.

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