Nature Communications (Mar 2023)

Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats

  • Keshav S. Subramanian,
  • Logan Tierno Lauer,
  • Anna M. R. Hayes,
  • Léa Décarie-Spain,
  • Kara McBurnett,
  • Anna C. Nourbash,
  • Kristen N. Donohue,
  • Alicia E. Kao,
  • Alexander G. Bashaw,
  • Denis Burdakov,
  • Emily E. Noble,
  • Lindsey A. Schier,
  • Scott E. Kanoski

DOI
https://doi.org/10.1038/s41467-023-37344-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

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Food intake is determined by learned appetitive responses and physiological “appetition” signals after eating begins. Here, authors show melanin-concentrating hormone (MCH)-producing neurons integrate these processes to promote caloric intake.