Nature Communications (Mar 2019)

Mesoscopic and microscopic imaging of sensory responses in the same animal

  • Davide Boido,
  • Ravi L. Rungta,
  • Bruno-Félix Osmanski,
  • Morgane Roche,
  • Tomokazu Tsurugizawa,
  • Denis Le Bihan,
  • Luisa Ciobanu,
  • Serge Charpak

DOI
https://doi.org/10.1038/s41467-019-09082-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Neuronal activity leads to a local increase in blood flow and volume, a process termed hyperaemia. Here, the authors employ multiple imaging approaches of neuronal and vascular activity at varying resolution to delineate the spatiotemporal dynamics of neurovascular coupling evoked by odours in the olfactory bulb.