Communications Biology (Sep 2022)
Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response
- Isabelle Weinhofer,
- Agnieszka Buda,
- Markus Kunze,
- Zsofia Palfi,
- Matthäus Traunfellner,
- Sarah Hesse,
- Andrea Villoria-Gonzalez,
- Jörg Hofmann,
- Simon Hametner,
- Günther Regelsberger,
- Ann B. Moser,
- Florian Eichler,
- Stephan Kemp,
- Jan Bauer,
- Jörn-Sven Kühl,
- Sonja Forss-Petter,
- Johannes Berger
Affiliations
- Isabelle Weinhofer
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Agnieszka Buda
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Markus Kunze
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Zsofia Palfi
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Matthäus Traunfellner
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Sarah Hesse
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Andrea Villoria-Gonzalez
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Jörg Hofmann
- Institute of Virology, Charité - Universitätsmedizin Berlin
- Simon Hametner
- Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna
- Günther Regelsberger
- Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna
- Ann B. Moser
- Department of Neurogenetics, Hugo W. Moser Research Institute at Kennedy Krieger, Kennedy Krieger Institute
- Florian Eichler
- Department of Neurology, Harvard Medical School, Massachusetts General Hospital
- Stephan Kemp
- Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam University Medical Center, Amsterdam Neuroscience, Amsterdam Gastroenterology Endocrinology Metabolism, University of Amsterdam
- Jan Bauer
- Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna
- Jörn-Sven Kühl
- Department of Pediatric Oncology, Hematology, and Hemostaseology, University Hospital Leipzig
- Sonja Forss-Petter
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- Johannes Berger
- Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna
- DOI
- https://doi.org/10.1038/s42003-022-03867-y
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 12
Abstract
Using Epstein-Barr virus (EBV) infection of human B cells, the importance of peroxisomal very long-chain fatty acid transport involving ABCD1 in viral infection and host defence is elucidated and applicable also to other herpes- and coronaviruses.
