Experimental Hematology & Oncology (Sep 2012)

A Japanese case of chronic lymphocytic leukemia with t (1;6)

  • Harada Kayo,
  • Ikeda Kazuhiko,
  • Matsumoto Hayato,
  • Furukawa Miki,
  • Takahashi Hiroshi,
  • Ohkawara Hiroshi,
  • Noji Hideyoshi,
  • Tasaki Kazuhiro,
  • Abe Masafumi,
  • Ogawa Kazuei,
  • Takeishi Yasuchika

DOI
https://doi.org/10.1186/2162-3619-1-28
Journal volume & issue
Vol. 1, no. 1
p. 28

Abstract

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Abstract Chronic lymphocytic leukemia (CLL) rarely exhibits an aggressive clinical course and its patients often have chromosomal deletions or additions. Furthermore, reciprocal translocations are barely observed in CLL. There have only been a few reports of CLL with t(1;6), and here we report the first Asian case of CLL with reciprocal translocation t(1;6). Since our case and previously reported CLL patients with t(1;6) consistently showed aggressive clinical course, t(1;6) may define a distinct type of CLL.

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