Pay more attention to the prognostic predictors of clinical high risk for psychosis

Abstract

Patients at clinical high risk (CHR) for psychosis are defined as individuals who manifest prodromal symptoms or genetic risk, as well as personality traits of psychosis. The risk of developing psychosis within 2 years is as high as 30% among CHR individuals. Therefore, predicting the individual risk of the transition to psychosis in this type of population has great significance in the early prevention of psychosis. In this article, we review the prognostic predictors of CHR from the perspectives of psychosocial factors, cognitive function, neuroimaging, neuroelectrophysiology and predictive models.

Keywords

• schizophrenia spectrum and other psychotic disorders
• prognosis
• risk factors
• review