Nature Communications (Jan 2021)
Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing
Abstract
The spontaneous bioelectrical activity of pacemaker cells in sinoatrial node (SAN) triggers the heartbeats. Here, the authors perform single-cell RNA sequencing in the mouse SAN and identify molecular and cellular features of the SAN conserved in rabbit and cynomolgus monkey, identifying a new potential SAN marker.