INFECTIOUS MONONUCLEOSIS AT CHILDREN: FEATURES OF THE COURSE OF THE DISEASE DEPENDING ON TYPES OF ANTIVIRAL THERAPY

Abstract

Purpose: The article contains results of the comparative analysis of dynamics of immunological parameters in the clinical period at children with an infectious mononucleosis of moderate severity during the acute period at treatment by the drugs “Anaferon kids “ and “Viferon” and further, in a catamnesis, within 6 years. The materials and methods: In group of research was 187 children. Three groups were created: the I group (n=75) – the patients receiving during the acute period «Anaferon kids» and pathogenetic therapy, the II group (n=72) – «Viferon» and pathogenetic therapy, the III group (n=40) – only with pathogenetic therapy. Results: Against the background of therapy with «Anaferon kids» and «Viferon» normalization of clinical symptoms and laboratory indicators came quicker in comparison with group of the children receiving only symptomatic therapy. At observation in a catamnesis, at all children the high rate of recurrent respiratory diseases was noted by viral infections. Changes in immunologic indicators became perceptible in all three groups throughout the entire period of observation.

Keywords

• infectious mononucleosis
• clinical picture
• immunology
• catamnesis