Mineralocorticoid receptor antagonists: new extended roles in cardio- and nephroprotection

Abstract

The article presents the contemporary views of the role of aldosterone in the progression of cardiovascular and renal diseases. It addresses matters related to the efficacy and safety of mineralocorticoid receptor antagonists in patients with chronic heart failure, chronic kidney disease at various stages including terminal renal failure, dialysis therapy, and kidney transplantation.

Keywords

• aldosterone
• mineralocorticoid receptor antagonists
• heart failure
• chronic kidney disease
• dialysis
• kidney transplantation