Mucin expression patterns in histological grades of colonic cancers in Ghanaian population

Kwabena Owusu Danquah; Ernest Adjei; Solomon Quayson; Ernest Adankwah; Daniel Gyamfi; Paul Poku Sampene Ossei; Gideon Dzikunu; Portia Mensah; Cecilia Lepkor

doi:10.11604/pamj.2017.27.267.9793

The Pan African Medical Journal (Aug 2017)

Mucin expression patterns in histological grades of colonic cancers in Ghanaian population

Kwabena Owusu Danquah,
Ernest Adjei,
Solomon Quayson,
Ernest Adankwah,
Daniel Gyamfi,
Paul Poku Sampene Ossei,
Gideon Dzikunu,
Portia Mensah,
Cecilia Lepkor

Affiliations

Kwabena Owusu Danquah: Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Ernest Adjei: Department of Pathology, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science andTechnology, Kumasi, Ghana
Solomon Quayson: Department of Pathology, Ghana Medical School, University of Ghana
Ernest Adankwah: Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Daniel Gyamfi: Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Paul Poku Sampene Ossei: Department of Pathology, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science andTechnology, Kumasi, Ghana
Gideon Dzikunu: Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Portia Mensah: Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Cecilia Lepkor: Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

DOI: https://doi.org/10.11604/pamj.2017.27.267.9793
Journal volume & issue: Vol. 27, no. 267

Abstract

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INTRODUCTION: Myriad roles of mucins in normal tissues have been well documented, including lubrication of the epithelial surfaces; protection from physical damage; facilitation in cell-cell signaling and suppression of inflammatory activity. Pathological expression of mucins has been noted in cancer development and progression. This study sought to identify and quantify the types of mucins produced during various histological grades of colon cancer and to assess the diagnostic significance.

Published in The Pan African Medical Journal

ISSN: 1937-8688 (Online)
Publisher: The Pan African Medical Journal
Country of publisher: Kenya
LCC subjects: Medicine
Website: https://panafrican-med-journal.com

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