Communications Biology (Jul 2022)
TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt
- Francisco J. Rios,
- Zhi-Guo Zou,
- Adam P. Harvey,
- Katie Y. Harvey,
- Livia L. Camargo,
- Karla B. Neves,
- Sarah E. F. Nichol,
- Rheure Alves-Lopes,
- Alexius Cheah,
- Maram Zahraa,
- Alexey G. Ryazanov,
- Lillia Ryazanova,
- Thomas Gudermann,
- Vladimir Chubanov,
- Augusto C. Montezano,
- Rhian M. Touyz
Affiliations
- Francisco J. Rios
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Zhi-Guo Zou
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Adam P. Harvey
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Katie Y. Harvey
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Livia L. Camargo
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Karla B. Neves
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Sarah E. F. Nichol
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Rheure Alves-Lopes
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Alexius Cheah
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Maram Zahraa
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Alexey G. Ryazanov
- Department of Pharmacology, Rutgers Robert Wood Johnson Medical School
- Lillia Ryazanova
- Lewis Sigler Institute of Integrative Genomics, Princeton University
- Thomas Gudermann
- Walther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München
- Vladimir Chubanov
- Walther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München
- Augusto C. Montezano
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- Rhian M. Touyz
- Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
- DOI
- https://doi.org/10.1038/s42003-022-03715-z
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
Deficiency of the Mg2+-permeable channel/α-kinase TRPM7 in mice increases susceptibility to cardiovascular and renal fibrosis induced by aldosterone and salt.
