International Medical Case Reports Journal (Sep 2018)

Successful treatment of prosthetic pulmonary valve thrombosis with reteplase: a case report

  • Khameneh Bagheri R,
  • Keihanian F,
  • Ahmadi M,
  • Ansari MA

Journal volume & issue
Vol. Volume 11
pp. 205 – 208

Abstract

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Ramin Khameneh Bagheri1 Faeze Keihanian,2,3 Mostafa Ahmadi,1 Mohammad Ali Ansari2 1Atherosclerosis Prevention Research Center, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 2Cardiology Department, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 3Pharmaceutical Research Division, Booali Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Abstract: Pulmonary prosthetic valve thrombosis is a serious and rare complication with high mortality. Using reteplase for treatment of prosthesis thrombosis is rarely reported. We report the first case in Iran of a thrombosed pulmonary valve in a patient who had undergone repair of tetralogy of Fallot, which was successfully treated twice with intravenous thrombolytic therapy with reteplase. Keywords: pulmonary valve thrombosis, reteplase, thrombolysis, recombinant plasminogen activator

Keywords