PLoS Medicine (Mar 2022)

A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies

  • Holly Q. Bennett,
  • Andrew Kingston,
  • Ilianna Lourida,
  • Louise Robinson,
  • Lynne Corner,
  • Carol Brayne,
  • Fiona E. Matthews,
  • Carol Jagger,
  • the Cognitive Function and Ageing Studies Collaboration

Journal volume & issue
Vol. 19, no. 3

Abstract

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Background Previous research has examined the improvements in healthy years if different health conditions are eliminated, but often with cross-sectional data, or for a limited number of conditions. We used longitudinal data to estimate disability-free life expectancy (DFLE) trends for older people with a broad number of health conditions, identify the conditions that would result in the greatest improvement in DFLE, and describe the contribution of the underlying transitions. Methods and findings The Cognitive Function and Ageing Studies (CFAS I and II) are both large population-based studies of those aged 65 years or over in England with identical sampling strategies (CFAS I response 81.7%, N = 7,635; CFAS II response 54.7%, N = 7,762). CFAS I baseline interviews were conducted in 1991 to 1993 and CFAS II baseline interviews in 2008 to 2011, both with 2 years of follow-up. Disability was measured using the modified Townsend activities of daily living scale. Long-term conditions (LTCs—arthritis, cognitive impairment, coronary heart disease (CHD), diabetes, hearing difficulties, peripheral vascular disease (PVD), respiratory difficulties, stroke, and vision impairment) were self-reported. Multistate models estimated life expectancy (LE) and DFLE, stratified by sex and study and adjusted for age. DFLE was estimated from the transitions between disability-free and disability states at the baseline and 2-year follow-up interviews, and LE was estimated from mortality transitions up to 4.5 years after baseline. In CFAS I, 60.8% were women and average age was 75.6 years; in CFAS II, 56.1% were women and average age was 76.4 years. Cognitive impairment was the only LTC whose prevalence decreased over time (odds ratio: 0.6, 95% confidence interval (CI): 0.5 to 0.6, p Conclusions In this study, we observed improvements to DFLE between 1991 and 2011 despite the presence of most health conditions we considered. Attention needs to be paid to support and care for people with cognitive impairment who had different outcomes to those with physical health conditions. Holly Bennett and colleagues investigate trends in life expectancy and disability-free life expectancy between 1991 and 2011 for adults age 65 years or older with long term health conditions using data from two population-based studies in England. Author summary Why was this study done? There have been many advances in healthcare since the 1990s, which means many people with health conditions are living longer lives. We wanted to find out whether the extension to life for those with health conditions involves an increase in healthy or unhealthy years. What did the researchers do and find? We used information from 2 large studies of people aged 65 years and over, the first began in 1991 and the second began in 2011. We estimated how many years people with different health conditions would live with or without disability in 2011 compared to 1991. We found improvements for people with most health conditions, with the exception of cognitive impairment where the increase in years lived with disability were equal (men) or greater than (women) the improvement in years lived without disability. What do these findings mean? In the UK, the percentage of people with cognitive impairment has decreased over time. However, if people with cognitive impairment are now living longer with disability than before, this may not mean that the demand for services and care will decrease.