康复学报 (Apr 2024)
Effect of Soft Rehabilitation Robot Gloves on Upper Limb and Hand Function of Stroke Patients：A Meta-Analysis
Abstract
ObjectiveTo evaluate the effect of soft rehabilitation robot gloves (SRG) on upper limb, hand motor function and activities of daily living of stroke patients by meta-analysis.MethodsData were searched and retrieved from the PubMed, Web of Science, The Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Wanfang Data, Chinese Biomedical Literature Service System (CBMdisc), Chinese Science and Technology Periodical Database (VIP). The randomized controlled trials (RCTs) of SRG intervention for patients with upper limb and hand motor dysfunction after stroke were included, and the retrieval time was from the database inception to August 2023.The primary outcome measures included Fugl-Meyer assessment of the upper extremity (FMA-UE), modified Barthel index (MBI), Wolf motor function test (WMFT), grip strength, box and block test (BBT) and action research arm test (ARAT). Two researchers independently completed data extraction and literature quality assessment, and meta-analysis was performed using RevMan 5.4 software. Continuous variables were expressed by mean difference (MD) or standardized mean difference (SMD) with 95% confidence interval (CI). The heterogeneity was determined according to the P value and I2 value. If P≥0.10 and I2≤50%, there was no heterogeneity or small heterogeneity among the studies, and a fixed effects model would be used, if P<0.1 and I2>50%, a random effects model would be used.ResultsA total of 13 RCTs with 653 patients were included. Meta-analysis results showed that, compared with the control group, FMA-UE score [MD=8.05, 95% CI (7.01,9.09), Z=15.20, P<0.000 01], MBI score [MD=9.91, 95% CI (2.65,17.17), Z=2.68, P=0.007], WMFT score [MD=8.39, 95% CI (6.99,9.78), Z=11.81，P<0.000 01], grip strength [SMD=0.39, 95% CI (0.11,0.67), Z=2.75, P=0.006], and ARAT score [MD=11.18, 95% CI (9.10, 13.26), Z=10.53, P<0.000 01] were significantly higher in the experimental group, but there was no significant difference in BBT score between two groups [MD=0.53, 95% CI (-1.47, 2.53), Z=0.52, P=0.60].ConclusionSRG can improve the upper limb and hand motor function and activities of daily living of stroke patients, but more large-sample and high-quality RCTs would be needed to further verify its efficacy.
