Escherichia albertii isolated from the bloodstream of a patient with liver cirrhosis in China: A case report
Qian Liu,
Hong Wang,
Suchuan Zhang,
Guodong Yan,
Xi Yang,
Xiangning Bai,
Jianping Deng,
Xi Chen,
Ling Zhang,
Jie Zhang,
Bin Wang,
Nianli Zou,
Yanwen Xiong,
Zhengdong Zhang
Affiliations
Qian Liu
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Hong Wang
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Suchuan Zhang
Zigong First Peoples Hospital, Zigong, Sichuan Province, China
Guodong Yan
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Xi Yang
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Xiangning Bai
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Jianping Deng
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Xi Chen
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Ling Zhang
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Jie Zhang
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Bin Wang
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Nianli Zou
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China
Yanwen Xiong
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China; Corresponding author
Zhengdong Zhang
Zigong Center for Disease Control and Prevention, Zigong, Sichuan Province, China; Corresponding author
A rare case of bacteremia caused by Escherichia albertii, in a 50-year-old male with liver cirrhosis was reported. Clear, colorless, and circular colonies were recovered on blood agar after 24 h of aerobic incubation at 37 °C. The isolate was identified as E. albertii using MALDI-TOF/MS and confirmed by the diagnostic triplex-PCR targeting clpX, lysP, and mdh genes. The administration of piperacillin/tazobactam intravenously (4.5g every 8 hours) for 3 days was effective. This study suggested that specific strains of E. albertii have been implicated in causing extraintestinal infections in humans, similar to extraintestinal pathogenic E. coli (ExPEC). However, a comprehensive understanding of the underlying pathogenic mechanisms requires further exploration.
