Comparison of vertical cup-disc ratio and disc damage likelihood scale with respect to visual field global indices in primary open-angle glaucoma patients: A cross-sectional study

Abstract

Background: In primary open-angle glaucoma (POAG), structural changes in optic nerve head precede functional changes in visual field (VF). Hence, it is important to detect glaucoma early as well as to monitor changes in glaucomatous damage. Aims: The aim of this study was to determine the correlation between each of vertical cup/disc ratio (VCDR) and the disc damage likelihood scale (DDLS) with global indices of Humphrey Field Analyzer II (HFA II). Methods: A total of 142 eyes of 71 patients diagnosed with POAG who fulfilled the inclusion and exclusion criteria were examined to grade DDLS score VCDR. HFA II Swedish Interactive Threshold Algorithm Standard 24-2 VFs were obtained. Statistical Analysis: The correlation of cup/disc (C/D) ratio with mean deviation (MD) and pattern standard deviation (PSD) was calculated by Spearman's correlation coefficient. Similar coefficients were obtained for DDLS also. Correlation values of selected variables were compared to find the difference in correlations. Results: DDLS shows strong negative correlation with MD (− 0.725) and strong positive correlation (0.625) with PSD when compared to C/D ratio. However, the differences between these correlations were not statistically significant. Conclusion: The DDLS shows stronger correlation with VF global indices than C/D ratio. Attention to disc diameter and rim width may increase the value of clinical optic disc examination

Keywords

• Disc damage likelihood scale
• global indices
• primary open-angle glaucoma
• vertical cup/disc ratio