ASSOCIATION BETWEEN SMOKING BEHAVIOUR AND GLYCOHEMOGLOBINE LEVELS AMONG ADULT JAVANESE INDONESIAN SMOKERS

Abstract

Nicotine, the active compound in cigarettes, can cause impaired glucose metabolism by increasing insulin resistance as well as decreasing insulin secretion in ? cell pancreas. This condition can increase the risk of type 2 diabetes in human. This study aims to evaluate the effect of smoking behaviour, determined by Cigarette per Day (CPD) and smoking duration, on glychohemoglobine (HbA1c) levels of Javanese Indonesian smokers. 30 smokers were studied consisting of 7 smokers with 10 CPD, 19 smokers with 11-20 CPD and 4 smokers with 21-30 CPD. They had been smoking for more than 10 years. The whole blood sample was used to examine the HbA1c levels. The HbA1c levels were tested at Bethesda Hospital's clinic laboratories using Architect 600 instrument. The results showed that CPD and smoking duration significantly influenced HbA1c, in which F count was F table (370.541 3.354) with significance 0.05 (2.35. 10-20 0.05) and multiple correlation coefficient (R) of 0.982. Therefore, based on this research finding, it was concluded that longer smoking duration and higher CPD caused higher smokers HbA1c level.

Keywords

• cpd
• hba1c
• smoking behaviour
• smoking duration.