JACC: Case Reports (Mar 2020)

Statin-Induced Necrotizing Autoimmune Myopathy

  • Brent Gawey, BS,
  • Manasi Tannu, MD MPH,
  • Jeeyon Rim, MD,
  • Laurence Sperling, MD,
  • Tracey L. Henry, MD, MPH, MS

Journal volume & issue
Vol. 2, no. 3
pp. 440 – 443

Abstract

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Statin-induced necrotizing autoimmune myopathy (SINAM) is an exceptionally rare yet devastating complication of statin therapy that can occur at any time after initiation. It should be considered in patients who develop proximal muscle weakness and marked elevated creatine phosphokinase while taking statin therapy. (Level of Difficulty: Beginner.)

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