Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus

Aleksandra Djokovic; Aleksandra Djokovic; Gordana Krljanac; Gordana Krljanac; Predrag Matic; Predrag Matic; Rastko Zivic; Rastko Zivic; Vuk Djulejic; Vuk Djulejic; Marija Marjanovic Haljilji; Dusan Popovic; Dusan Popovic; Branka Filipovic; Branka Filipovic; Svetlana Apostolovic; Svetlana Apostolovic

doi:10.3389/fcvm.2023.1260478

Frontiers in Cardiovascular Medicine (Oct 2023)

Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus

Aleksandra Djokovic,
Aleksandra Djokovic,
Gordana Krljanac,
Gordana Krljanac,
Predrag Matic,
Predrag Matic,
Rastko Zivic,
Rastko Zivic,
Vuk Djulejic,
Vuk Djulejic,
Marija Marjanovic Haljilji,
Dusan Popovic,
Dusan Popovic,
Branka Filipovic,
Branka Filipovic,
Svetlana Apostolovic,
Svetlana Apostolovic

Affiliations

Aleksandra Djokovic: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Aleksandra Djokovic: Department of Cardiology, University Hospital Center Bezanijska Kosa, Belgrade, Serbia
Gordana Krljanac: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Gordana Krljanac: Cardiology Clinic, University Clinical Center of Serbia, Belgrade, Serbia
Predrag Matic: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Predrag Matic: Clinic for Vascular Surgery, Institute for Cardiovascular Diseases “Dedinje”, Belgrade, Serbia
Rastko Zivic: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Rastko Zivic: Department for Surgery, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbia
Vuk Djulejic: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Vuk Djulejic: Faculty of Medicine, Institute of Anatomy, Belgrade, Serbia
Marija Marjanovic Haljilji: Department for Gastroenterology, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbia
Dusan Popovic: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Dusan Popovic: Department for Gastroenterology, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbia
Branka Filipovic: Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Branka Filipovic: Department for Gastroenterology, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbia
Svetlana Apostolovic: Coronary Care Unit, Cardiology Clinic, University Clinical Center of Nis, Nis, Serbia
Svetlana Apostolovic: Faculty of Medicine, University of Nis, Nis, Serbia

DOI: https://doi.org/10.3389/fcvm.2023.1260478
Journal volume & issue: Vol. 10

Abstract

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Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions.

Published in Frontiers in Cardiovascular Medicine

ISSN: 2297-055X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.frontiersin.org/journals/cardiovascular-medicine

About the journal

Abstract

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