Majalah Kedokteran Andalas (Jul 2021)

The Effect of Mesenchymal Stem Cell Wharton Jelly on Alzheimer’s Rat with Y-Maze Test Method

  • Sisca Dwi Yarni,
  • Hirowati Ali,
  • Djong Hon Tjong

DOI
https://doi.org/10.25077/mka.v44.i2.p112-116.2021
Journal volume & issue
Vol. 44, no. 2
pp. 112 – 116

Abstract

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Objective: This study aims to examine the y-maze test in alzheimer's rat after giving mesenchymal stem cell wharton jelly. Methods: This study used the y-maze test method to test the cognitive test of rat with the Y arm model. The treatment group consisted of a control, AlCl3, MSC-WJ and a combination of AlCl3 and MSC-WJ. The results obtained were analyzed in the form of a percentage. Results: The results of this study showed that the y-maze test showed that MSC-WJ had a significant effect compared to the AlCl3 control group in the alzheimer’s rat, namely 51.33% and 12.31%. Conclusion: In this study it was concluded that that MSC-WJ has a significant effect on alzheimer’s rat with y maze test. Keywords: AlCl3; Alzheimer’s; Mesenchymal Stem Cell Wharton Jelly

Keywords