The FEDBD plasma’s quantitative investigation of skin parameters: Skin elasticity, thickness, density, tissue oxygenation, perfusion, and edema
Parisa Charipoor,
Mohammad Ali Nilforoushzadeh,
Mohammadreza Khani,
Maryam Nouri,
Erfan Ghasemi,
Mohammad Amir Amirkhani,
Mohammad Eftekhari,
Babak Shokri
Affiliations
Parisa Charipoor
Laser-Plasma Research Institute, Shahid Beheshti University, G.C., P.O. Box, 19839-6941, Tehran, Iran
Mohammad Ali Nilforoushzadeh
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran; Skin Repair Research Center, Jordan Dermatology and Hair Transplantation Center, Tehran, Iran
Mohammadreza Khani
Laser-Plasma Research Institute, Shahid Beheshti University, G.C., P.O. Box, 19839-6941, Tehran, Iran; Corresponding author.
Maryam Nouri
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran; Skin Repair Research Center, Jordan Dermatology and Hair Transplantation Center, Tehran, Iran; Corresponding author.
Erfan Ghasemi
Laser-Plasma Research Institute, Shahid Beheshti University, G.C., P.O. Box, 19839-6941, Tehran, Iran
Mohammad Amir Amirkhani
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran; Skin Repair Research Center, Jordan Dermatology and Hair Transplantation Center, Tehran, Iran
Mohammad Eftekhari
Laser-Plasma Research Institute, Shahid Beheshti University, G.C., P.O. Box, 19839-6941, Tehran, Iran
Babak Shokri
Laser-Plasma Research Institute, Shahid Beheshti University, G.C., P.O. Box, 19839-6941, Tehran, Iran; Physics Department of Shahid Beheshti University, G.C., P.O. Box, Tehran, 19839-6941, Iran
This study used the FEDBD plasma device for skin rejuvenation in animal samples. There were two groups of six male Wistar rats. Before starting the treatment, immediately after the treatment, the fourth week, and the tenth week of follow-up, biometric tests were performed, including moisture level, evaporation from the skin surface, erythema and melanin, skin elasticity and firmness with an MPA9 device and cutometer. The thickness and density of the epidermis and dermis, an essential indicator in rejuvenation, were evaluated with a skin ultrasound device. Also, the level of oxygen, perfusion, and interstitial water (edema) was checked using a Tivita tissue hyperspectral camera at a depth of 6 mm of the skin.
