Video Images about Decisions for Ethical Outcomes in Kidney Disease (VIDEO-KD): the study protocol for a multi-centre randomised controlled trial
Yuchiao Chang,
Joshua R Lakin,
Michael K Paasche-Orlow,
Charlotta Lindvall,
Areej El-Jawahri,
Angelo Volandes,
Aretha Delight Davis,
Margaret K Yu,
Nwamaka D Eneanya,
Susan P Y Wong,
Sushrut S Waikar,
Edward T Moseley,
Lori Henault,
Amresh D Hanchate,
Ernest I Mandel,
Sophia N Zupanc,
Lisa M Quintiliani,
Amar D Bansal,
Jane O Schell,
Andrew L Lundquist,
Manjula Kurella Tamura,
Mark L Unruh,
Christos Argyropoulos,
Michael J Germain
Affiliations
Yuchiao Chang
Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
Joshua R Lakin
Harvard Medical School, Boston, Massachusetts, USA
Michael K Paasche-Orlow
Boston University School of Medicine, Section of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, USA
Charlotta Lindvall
Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA
Areej El-Jawahri
Harvard Medical School, Boston, Massachusetts, USA
Angelo Volandes
Harvard Medical School, Boston, Massachusetts, USA
Aretha Delight Davis
ACP Decisions, Waban, Massachusetts, USA
Margaret K Yu
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
Nwamaka D Eneanya
Renal-Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Susan P Y Wong
University of Washington, Seattle, Washington State, USA
Sushrut S Waikar
Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA
Edward T Moseley
Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
Lori Henault
Boston University School of Medicine, Section of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, USA
Amresh D Hanchate
Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
Ernest I Mandel
Harvard Medical School, Boston, Massachusetts, USA
Sophia N Zupanc
Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
Lisa M Quintiliani
Boston University School of Medicine, Section of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, USA
Amar D Bansal
Division of Nephrology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Jane O Schell
Section of Palliative Care and Medical Ethics, Division of Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Andrew L Lundquist
Harvard Medical School, Boston, Massachusetts, USA
Manjula Kurella Tamura
Division of Nephrology, Stanford University School of Medicine; and Geriatric Research Education Clinical Center, VA Palo Alto Health Care System, Palo Alto, California, USA
Mark L Unruh
Department of Medicine, University of New Mexico, Albuquerque, New Mexico, USA
Christos Argyropoulos
Division of Nephrology, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
Michael J Germain
Baystate Medical Center-University of Massachusetts Springfield, Springfield, Massachusetts, USA
Introduction Older patients with advanced chronic kidney disease (CKD) often are inadequately prepared to make informed decisions about treatments including dialysis and cardiopulmonary resuscitation. Further, evidence shows that patients with advanced CKD do not commonly engage in advance care planning (ACP), may suffer from poor quality of life, and may be exposed to end-of-life care that is not concordant with their goals. We aim to study the effectiveness of a video intervention on ACP, treatment preferences and other patient-reported outcomes.Methods and analysis The Video Images about Decisions for Ethical Outcomes in Kidney Disease trial is a multi-centre randomised controlled trial that will test the effectiveness of an intervention that includes a CKD-related video decision aid followed by recording personal video declarations about goals of care and treatment preferences in older adults with advancing CKD. We aim to enrol 600 patients over 5 years at 10 sites.Ethics and dissemination Regulatory and ethical aspects of this trial include a single Institutional Review Board mechanism for approval, data use agreements among sites, and a Data Safety and Monitoring Board. We intend to disseminate findings at national meetings and publish our results.Trial registration number NCT04347629.
