Stereoselective gold(I)-catalyzed approach to the synthesis of complex α-glycosyl phosphosaccharides

Abstract

Glycosyl phosphosaccharides represent a large and important family of complex glycans, but are difficult to synthesize efficiently. Here, the authors disclose a stereoselective methodology to make α-glycosyl phosphosaccharides, via gold(I)-catalyzed glycosylation of phosphoric acid acceptors.