SYNTHESIS, STUDIES THEIR QUANTUM MECHANICAL PROPERTIES AND BIOLOGICAL ACTIVITY OF NEWER ANTIPYRIN DERIVATIVE AND ITS (CU2+) COMPLEX

Abstract

The synthesis of (C16H14N3O2) ligand and (Cu2C32H28N6O12S2) complex are prepared in this work . The newly prepared compounds were characterized by IR spectroscopy and elemental analysis . The determination of the antimicrobial activity of ligand and its complex was carried out on sample of Escherichia coli , Klebsiella pneumonia , Staphylococcus aureus and Bacillus cereus . The quantitative antimicrobial activity test results proved that all the prepared compounds are very active against Bacillus cereus and that complex very active against Escherichia coli.. Quantum mechanical calculation confirmed the assumption of stability of prepared compounds which agreement with antimicrobial activity results .

Keywords

• klebsiella
• staphylococcus
• escherichia coli