Nature Communications (Mar 2020)

Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections

  • Aimen Zlitni,
  • Gayatri Gowrishankar,
  • Idan Steinberg,
  • Tom Haywood,
  • Sanjiv Sam Gambhir

DOI
https://doi.org/10.1038/s41467-020-14985-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Sensitive diagnostic tools for bacterial infections of wounds and surgical sites are necessary to enable early detection and determine optimal means of treatment. Here, the authors develop a fluorescent and optoacoustic probe based on a maltotriose scaffold, which is selectively taken up by gram-positive and gram-negative bacteria.