Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes

Yan Yang; Guoyu Liu; Feng Li; Lucas B. Carey; Changjin Sun; Kaiping Ling; Hiroyuki Tachikawa; Morihisa Fujita; Xiao-Dong Gao; Hideki Nakanishi

doi:10.1038/s42003-022-03791-1

Communications Biology (Aug 2022)

Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes

Yan Yang,
Guoyu Liu,
Feng Li,
Lucas B. Carey,
Changjin Sun,
Kaiping Ling,
Hiroyuki Tachikawa,
Morihisa Fujita,
Xiao-Dong Gao,
Hideki Nakanishi

Affiliations

Yan Yang: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Guoyu Liu: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Feng Li: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Lucas B. Carey: Center for Quantitative Biology and Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University
Changjin Sun: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Kaiping Ling: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Hiroyuki Tachikawa: Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, University of Tokyo
Morihisa Fujita: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Xiao-Dong Gao: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Hideki Nakanishi: Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University

DOI: https://doi.org/10.1038/s42003-022-03791-1
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 15

Abstract

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The multiligand receptor RAGE (receptor for advanced glycation end-products) mediates phagocytosis in non-professional phagocytes (NPPs), for example through the use of RNA fragments as ligands for internalization.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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