Bowel Perforation in a Patient with Hepatocellular Carcinoma during Lenvatinib Treatment

Abstract

We present a case of severe bowel perforation during lenvatinib treatment for advanced hepatocellular carcinoma. Although the Hartmann’s procedure was performed, the patient died 48 h after the operation. The histopathological findings suggested that lenvatinib was involved in the etiology of bowel perforation in this case.

Keywords

• lenvatinib
• bowel perforation
• hepatocellular carcinoma