53BP1: guarding the genome with a novel liquid weapon

Naveen Kumar Tangudu; Katherine M. Aird

doi:10.1038/s42003-022-03401-0

Communications Biology (May 2022)

53BP1: guarding the genome with a novel liquid weapon

Naveen Kumar Tangudu,
Katherine M. Aird

Affiliations

Naveen Kumar Tangudu: Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine
Katherine M. Aird: Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine

DOI: https://doi.org/10.1038/s42003-022-03401-0
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 3

Abstract

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In this Comment, Naveen Tangudu and Katherine Aird discuss recent findings showing that 53BP1 regulates heterochromatin through liquid-liquid phase separation.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal