Value of preoperative CT evaluation of extramural vascular invasion in evaluating the prognosis of gastric cancer patients

Abstract

Objective To investigate the value of preoperative CT evaluation of extramural vascular invasion in evaluating the prognosis of gastric cancer patients. Methods The patients who underwent gastrectomy in our hospital from January 2016 to December 2018 were enrolled as subjects, and preoperative CT examination was performed to evaluate extramural vascular invasion. The patients were followed up after surgery to observe overall survival (OS) and disease-free survival (DFS); the K-M curve and the log-rank test were used to analyze the association of extramural vascular invasion with OS and DFS, and the COX regression model was used to investigate the influencing factors for OS and DFS. Results The patients with a tumor diameter of ≥5 cm and TNM stage Ⅲ gastric cancer had a significantly higher incidence rate of extramural vascular invasion on preoperative CT evaluation than those with a tumor diameter of <5 cm and TNM stage Ⅰ-Ⅱ gastric cancer (χ2=7.745,7.011,P<0.05). Compared with the gastric cancer patients without extramural vascular invasion on preoperative CT evaluation, the patients with extramural vascular invasion had significantly shorter DFS and OS (χ2=6.245,5.388,P<0.05). Extramural vascular invasion and TNM stage were the influencing factors for DFS, and extramural vascular invasion, tumor diameter, and TNM stage were the influencing factors for OS in gastric cancer patients. Conclusion Preoperative CT evaluation of extramural vascular invasion is of great value in evaluating the prognosis of patients with gastric cancer.

Keywords

• stomach neoplasms|tomography, x-ray computed|neoplasm invasiveness|blood vessels|pathological conditions, signs and symptoms|proportional hazards models|root cause analysis|prognosis