Revista da Sociedade Brasileira de Medicina Tropical (Feb 2021)

Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti

  • Fernando Cesar Martins Betim,
  • Camila Freitas de Oliveira,
  • Deise Prehs Montrucchio,
  • Obdulio Gomes Miguel,
  • Marilis Dallarmi Miguel,
  • Juliana Bello Baron Maurer,
  • Josiane de Fátima Gaspari Dias

DOI
https://doi.org/10.1590/0037-8682-0576-2020
Journal volume & issue
Vol. 54

Abstract

Read online

Abstract INTRODUCTION: Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum. METHODS: The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples. RESULTS: S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae). CONCLUSIONS Extracts from O. nutans were effective against third-stage larvae ofA. aegyptiafter 24 h of exposure.

Keywords