The Effect of Prognostic Nutritional Index on Prognosis in Small Cell Lung Cancer: Single Center Experience

Abstract

Aim:The aim of this study is to investigate the effect of prognostic nutritional index parameter on overall survival in small cell lung cancer patients.Materials and Methods:Fifty-two small cell lung cancer patients who were diagnosed in our clinic were reviewed retrospectively. Prognostic nutritional index (PNI) was calculated using albumin and lymphocyte value at the time of diagnosis. The relationship between PNI and overall survival was examined.Results:Of the 52 patients in our study, 47 were male and 5 were female. The median age was 62.9 years.The median PNI value was 45. Median progression-free survival was 6.9 months, median overall survival was 8.7 months. In the multivariate analysis, limited stage disease and PNI≥45 were found to be an independent good prognostic factor for overall survival. There was no relationship between overall survival and gender, age, and LDH status.Conclusion:In our study, we found that the prognostic nutritional index and limited stage disease are good prognostic factors in terms of overall survival.

Keywords

• small cell lung cancer
• prognostic nutritional index
• overall survival