Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.

Abstract

In the kingdom Plantae, bryophytes have the second-largest taxonomic group. These bryophytes are very limited and dispersed, so studies are conducted to understand their chemical composition. In this study, Total phenolic content (TPC), Total flavonoid content (TFC), Gas-chromatography and Mass spectroscopy (GC–MS) analysis, and cytotoxic activities of different extracts from B. javanica have been tested. TPC and TFC showed higher yields in methanol than in n-hexane. It has also demonstrated six phytoconstituents in methanolic extracts, and cytotoxicity activity has been tested in which B. javanica depending on dose, had shown an antiproliferative effect on CRC cells. This present study reviews existing research and recommends additional studies to assess the cytotoxic effects of bryophytes.

Keywords

• Bryophytes
• Moss
• Phenol
• GC–MS activity
• Cytotoxicity
• XTT assay