Nature Communications (Apr 2022)
Low complexity RGG-motif sequence is required for Processing body (P-body) disassembly
Abstract
Processing bodies (PBs) are higher order RNA-protein complexes that determine mRNA fate. Here, the authors show Sbp1 is responsible for PB disassembly and pinpoint a repeats of arginine and glycine (RGG) motif in Sbp1 that play a key role.