Heliyon (Mar 2024)
Associations between sleep problems and cardiometabolic risk in maintenance hemodialysis patients: A multicenter study
- Huan Yang,
- Yingxin Zhang,
- Xiuyong Li,
- Zhi Liu,
- Youwei Bai,
- Guangrong Qian,
- Han Wu,
- Ji Li,
- Yuwen Guo,
- Shanfei Yang,
- Lei Chen,
- Jian Yang,
- Jiuhuai Han,
- Shengyin Ma,
- Jing Yang,
- Linfei Yu,
- Runzhi Shui,
- Xiping Jin,
- Hongyu Wang,
- Fan Zhang,
- Tianhao Chen,
- Xinke Li,
- Xiaoying Zong,
- Li Liu,
- Jihui Fan,
- Wei Wang,
- Yong Zhang,
- Guangcai Shi,
- Deguang Wang,
- Shuman Tao
Affiliations
- Huan Yang
- Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China
- Yingxin Zhang
- Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China
- Xiuyong Li
- Blood Purification Center, NO.2 People's Hospital of Fuyang City, 1088 Yinghe West Road, Fuyang, 236015, China
- Zhi Liu
- Department of Nephrology, The First Affiliated Hospital of Anhui University of Science & Technology, 203 Huaibin Road, Huainan, 232000, China
- Youwei Bai
- Department of Nephrology, The Second People's Hospital of Lu'an City, 73 Mozitan Road, Lu'an, 237000, China
- Guangrong Qian
- Department of Nephrology, Maanshan People's Hospital, 45 Hubei Road, Maanshan, 243099, China
- Han Wu
- Blood Purification Center, Bozhou People's Hospital, 616 Duzhong Road, Bozhou, 236814, China
- Ji Li
- Department of Nephrology, Tongling People's Hospital, 468 Bijiashan Road, Tongling, 244099, China
- Yuwen Guo
- Department of Nephrology, Lujiang County People's Hospital, 32 Wenmingzhong Road, Lujiang, 231501, China
- Shanfei Yang
- Department of Nephrology, Shouxian County Hospital, Northeast of the Intersection of Binyang Avenue and Dongjin Avenue, Shouxian County, 232200, China
- Lei Chen
- Department of Nephrology, Hefei Jinnan Kidney Hospital, Northeast of the Intersection of Fozhang Road and Beihai Road, Hefei, 230071, China
- Jian Yang
- Department of Nephrology, Funan County People's Hospital, 36 Santa Road, Funan County, 236300, China
- Jiuhuai Han
- Department of Nephrology, Anqing Municipal Hospital, 87 East Tianzhushan Road, Anqing, 246003, China
- Shengyin Ma
- Department of Nephrology, Anhui Wanbei Coal-Electricity Group General Hospital, 125 Huaihe West Road, Suzhou, 234099, China
- Jing Yang
- Department of Nephrology, The First People's Hospital of Hefei, 390 Huaihe Road, Hefei, 230061, China
- Linfei Yu
- Department of Nephrology, The People's Hospital of Taihu, 196 Renmin Road, Taihu County, 246400, China
- Runzhi Shui
- Blood Purification Center, Huangshan City People's Hospital, 4 Liyuan Road, Huangshan, 245000, China
- Xiping Jin
- Department of Nephrology, Huainan Chao Yang Hospital, 15 Renmin South Road, Huainan, 232007, China
- Hongyu Wang
- Department of Nephrology, Lixin County People's Hospital, Intersection of Wenzhou Road and Feihe Road, Lixin County, 236700, China
- Fan Zhang
- Department of Nephrology, Dongzhi County People's Hospital, 70 Jianshe Road, Dongzhi County, 247299, China
- Tianhao Chen
- Department of Nephrology, Tianchang City People's Hospital, 137 Jianshe East Road, Tianchang, 239399, China
- Xinke Li
- Department of Nephrology, Xiaoxian People's Hospital, 58 Jiankang Road, Xiaoxian Conty, 235200, China
- Xiaoying Zong
- Department of Nephrology, The Second Affiliated Hospital of Bengbu Medical College, 633 Longhua Road, Bengbu, 233017, China
- Li Liu
- Department of Nephrology, The Second People's Hospital of Hefei, 246 Heping Road, Hefei, 230012, China
- Jihui Fan
- Department of Nephrology, Huaibei People's Hospital, 66 Huaihai West Road, Huaibei, 235000, China
- Wei Wang
- Department of Nephrology, The People's Hospital of Xuancheng City, 51 Dabatang Road, Xuancheng, 242099, China
- Yong Zhang
- Department of Nephrology, Lujiang County Hospital of TCM, 350 Zhouyu Avenue, Lujiang County, 231501, China
- Guangcai Shi
- Department of Nephrology, The Fifth People's Hospital of Hefei, Yuxi Road, Hefei, 230011, China
- Deguang Wang
- Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China; Corresponding author.
- Shuman Tao
- Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China; Corresponding author.
- Journal volume & issue
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Vol. 10,
no. 6
p. e27377
Abstract
The incidence of cardiovascular disease is increasing around the world, and it is one of the main causes of death in chronic kidney diseases patients. It is urgent to early identify the factors of cardiometabolic risk. Sleep problems have been recognized as a risk factor for cardiometabolic risk in both healthy people and chronic patients. However, the relationship between sleep problems and cardiometabolic risk has not been clearly explored in hemodialysis patients. This study aimed to investigate the relationship between sleep problems and cardiometabolic risk in 3025 hemodialysis patients by a multicenter study. After adjusting for confounders, binary logistic regression models showed that hemodialysis patients reported sleep duration greater than 7 h were more likely to be with hypertension, hyperglycemia, hypertriglyceridemia, and hypercholesterolemia. Patients reported sleep duration less than 7 h were more likely to be with hypertriglyceridemia and hypercholesterolemia, but the risks of hyperglycemia and Low HDL-cholesterol were decreased. Poor sleep quality was negatively correlated to low HDL cholesterol and hypertriglyceridemia. Moreover, gender-based differences were explained.
