SECONDARY SOLID TUMORS IN CHILDREN AFTER ALLOGENEIC HEMATOPOIETIC STEM CELLS TRANSPLANTATION: CASE REPORTS AND LITERATURE REVIEW

Abstract

Allogeneic hematopoietic stem cell transplantation (HSCT) is an effective approach to cure numerous malignant and nonmalignant diseases. This method is more available now, respectively the number of survivors – recipients of HSCT increases every year. Among long-term complications of HSCT secondary solid cancers are one of the most life-threatening. We discuss different types of secondary solid tumours after HSCT and describe international recommendations of their screening and diagnostic. Several case reports from the single center could illustrate these serious late effects.

Keywords

• allogeneic hematopoietic stem cell transplantation
• late effects
• secondary solid tumours